The typical adult dosage for cold sore treatment is 2 g every 12 hours for one day, but your doctor may adjust your dosage to accommodate your specific needs. Valtrex therapy may be started after a cold sore has erupted, but the best treatment results are achieved by beginning Valtrex therapy at the first signs of a cold sore, such as tingling, burning or blisters. Valtrex (valacyclovir) is an antiviral medication used to treat infections with: herpes zoster , herpes simplex genitalis (genital herpes), and herpes labialis. Valtrex is available in generic form. We provide full service adult Valtrex For Two Days in a meticulously clean environment with state-of-the-art equipment. Dr. Sharp and his staff strive to provide consistently exceptional results whether your treatment requires implants, complicated bridgework, treatment for gum disease, dentures or simply routine restorations. In a third trial, subjects were randomized to receive VALTREX 500 mg twice daily for 5 days (n = 398) or VALTREX 500 mg twice daily for 3 days (and matching placebo twice daily for 2 additional days) (n = 402). The median time to lesion healing was about 4½ days in both treatment groups. The median time to cessation of pain was about 3 days in both treatment groups. Valtrex is more effective if taken within 1-2 days after the symptoms start. Take Valtrex with a full glass of water. Water is very important when taking Valtrex so the kidneys keep working. In a third trial, subjects were randomized to receive Valtrex 500 mg twice daily for 5 days (n = 398) or Valtrex 500 mg twice daily for 3 days (and matching placebo twice daily for 2 additional days) (n = 402). The median time to lesion healing was about 4½ days in both treatment groups. The median time to cessation of pain was about 3 days in both treatment groups. 2 grams every 12 hours for 1 day. Genital Herpes : Initial episode. 1 gram twice daily for 10 days. Recurrent episodes : 500 mg twice daily for 3 days VALTREX may be given without regard to meals. • Valacyclovir oral suspension (25 mg/mL or 50 mg/mL) may be prepared extemporaneously from 500-mg VALTREX Caplets for use in pediatric patients for whom a solid dosage form is not appropriate [see Dosage and Administration (2.3)]. It can take up to 10 days (or, in some cases, even longer) for herpes blisters to heal even with valacyclovir treatment. This makes it important to start treatment as soon as you notice herpes symptoms. Valtrex; Reviews. Valtrex Reviews. 36. 500mg at first sight of outbreak for 2 days. I just got an outbreak today and woke up to blisters already. It works best at the tingle, anytime after that.